Chemokin cxcl13

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August undefined, 2024

WebNov 1, 2010 · The chemokine CXCL13 is used as complement to serology in the diagnostics of Lyme neuroborreliosis (LNB). We evaluated and compared the semi-quantitative, cassette-based ReaScan CXCL13 assay with ... WebOct 10, 2024 · CXCL13 may thus serve as a potential novel target in MM. Altogether, our findings suggest that bidirectional interactions of MΦ with MM tumor cells result in M2 MΦ polarization, CXCL13 induction, and subsequent OC activation, enhancing their ability to …

CXCL13 - an overview ScienceDirect Topics

WebJan 12, 2024 · CXCL13 is a potent B-cell chemoattractant chemokine, which has a crucial role in the recruitment and trafficking of B cells after interaction with its receptor CXCR5. This study is aimed to evaluate plasma levels of CXCL13 and its receptor CXCR5 in Saudi patients with asthma exacerbation relative to healthy controls. WebMar 21, 2024 · CXCL13 (C-X-C Motif Chemokine Ligand 13) is a Protein Coding gene. Diseases associated with CXCL13 include Angioimmunoblastic T-Cell Lymphoma and Neurosyphilis . Among its … is bing backed by gpt-4

Chemokine CXCL13 - an overview ScienceDirect Topics

WebNov 13, 2015 · Here, we screened for abnormal inflammatory factors in non-small cell lung cancers (NSCLCs) from Xuanwei and control regions (CR) where smoky coal was not used, and found that a chemokine CXCL13 was overexpressed in 63/70 (90%) of Xuanwei NSCLCs and 44/71 (62%) of smoker and 27/60 (45%) of non-smoker CR patients. WebCXCR5 is the receptor for the chemokine CXCL13, the chemokine important for secondary lymphoid tissue orchestration and lymphoid neogenesis. CXCL13 is constitutively expressed in secondary lymphoid tissue (Cyster et al., 2000) primarily by follicular dendritic cells in the spleen, lymph nodes, tonsils, and Peyer's patches ( Cyster et al., 2000 ... WebOct 8, 2009 · Furthermore, autocrine/paracrine activation of chemokine receptor-7 (CCR7) in HNSCC has been shown to mediate cell survival and metastasis. 30 Inflammatory cytokines such as IL-1β have been shown to induce CXCL13 production in differentiated osteoblasts 31 and human osteoblasts have been shown to express functional CXCR3 … is bing based on chatgpt

ELR positive CXCL chemokines are highly expressed in an animal …

Long non-coding RNA maternally expressed gene 3, miR …

WebSep 27, 2009 · The chemokines CXCL13 ( A000378 ), CCL19 and CCL21 ( A002167) are involved in LTi cell homing and lymph node development 15, 16. Lack of the genes encoding CCL21 and CCL19 or their receptor,... WebApr 12, 2024 · CXCL13, a B-cell chemokine produced mainly by mesenchymal lymphoid tissue organizer cells, follicular dendritic cells, and human T follicular helper cells, was found to be linked to a number of ... is bing becoming better than googleWebRecently, the chemokine CXCL13 has been shown to be expressed in 90% of AILTCL, but only in 10% of peripheral T-cell lymphoma, NOS. Disrupted and expanded FDC networks can be recognized using antibodies to CD21, CD35, and clusterin, a feature that helps to … is bing becoming more popular than google

"CXCL13 is a small chemokine belonging to the CXC chemokine family. As its other names suggest, this chemokine is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization … See more Chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a protein ligand that in humans is encoded by the CXCL13 gene See more • Human CXCL13 genome location and CXCL13 gene details page in the UCSC Genome Browser. • Overview of all the structural … See more " - Chemokin cxcl13

Chemokin cxcl13

WebJul 22, 2024 · In this study we focus on the chemokine CXCL13, a small globular protein with a theoretical average mass of 10.31 kDa that has emerged as a key regulator of B-cell migration and lymphoid tissue ... WebNov 10, 2024 · CCL4 (CC chemokine ligand 4), CXCL4 (CXC chemokine ligand 4), CXCL7 (CXC chemokine ligand 7), and CXCL13 (CXC chemokine ligand 13) are expressed in the early stage, while CCL3 (CC chemokine ligand 3) and CCL9 (CC chemokine ligand 9) are expressed in more advanced stages of the disease . On the other hand, uncontrolled …

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WebCXCL13 [also known as B-cell-attracting chemokine 1 (BCA1)] and CXCR5 comprise a monogamous ligand–receptor pair critical for the homeostatic organization of B-cell zones of secondary lymphoid tissue. CXCR5 has been detected on all peripheral blood and tonsillar B cells, but on only a fraction of cord blood and bone marrow B cells. WebCompared with younger mice, injured DRG sensory neurons in older mice expressed higher levels of the chemokine CXCL13, which attracted CXR5 + CD8 + T cells. T cell–neuron cross-talk activated caspase 3, which impaired pAKT, and pS6 signaling causing regenerative failure. When caspase 3, CXCR5, or CXCL13 was therapeutically targeted, …

Web23 hours ago · CXCL13, chemokine C-X-C motif ligand 13; CXCR5, C-X-C chemokine receptor type 5; IL-3, interleukin 3; TGF- β, transforming growth factor beta. Figure 3. View large Download PPT. Overview of cross talk between tumor cells and noncancerous immune cells in the TME of CHL. WebIn addition, other chemokines of this group including CXCL1, CXCL2, and CXCL7 had a significant increase compared to the control group (P≤0.05). However, ELR −, CXC chemokines such as CXCL4, CXCL13, and CXCL16 showed a smaller upregulation, while CXCL14 chemokine showed a significant decrease compared to the control group …

WebNov 13, 2015 · Here, we screened for abnormal inflammatory factors in non-small cell lung cancers (NSCLCs) from Xuanwei and control regions (CR) where smoky coal was not used, and found that a chemokine CXCL13 … WebCXCL12, CXCL13, and BAFF are markers of B cell activation in neuroinflammatory CNS disorders; 8,21 however, the mechanisms and consequences of elevated CXCL12 could be complicated due to multiple modulatory mechanisms, such as changes in expression, bioavailability, and post-translational modifications, as well as changes in its receptors …

WebSep 1, 2009 · Retinoic acid induces the expression of chemokine CXCL13 via RARβ (a) CXCL13, CCL21, VCAM1, and Madcam1 mRNA in E13.5 Bl/6 embryonic cells in the presence of RA for 6h compared to untreated cells ...

WebJul 15, 2006 · The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis Blood American Society of Hematology Supplemental data CHEMOKINES, CYTOKINES, AND INTERLEUKINS July 15, 2006 The chemokine CXCL13 is a key molecule in … is bing better than braveWebCXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It … is bing better than duckduckgoWebFeb 24, 2024 · The CXCL13 negative category included two subgroups with normal and dysfunctional BCSFB. Results: Despite clear evidence in serum, CXCL13 was detectable only at trace amounts (medians 3.5 and 7.5 pg/ml) in CSF of the two CXCL13 negative … is bing becoming betterWebThe development of cancer is a multistep and complex process involving interactions between tumor cells and the tumor microenvironment (TME). C-X-C chemokine ligand 13 (CXCL13) and its receptor, CXCR5, make crucial contributions to this process by … is bing becoming more popularWebNov 26, 2024 · The chemokine CXC ligand 13 protein (CXCL13), also known as B cell-attracting chemokine-1 (BAC-1) or B lymphocyte chemoattractant (BLC), is a CXC subtype member of the chemokine superfamily. The receptor of CXCL13 is CXCR5, which is … is bing better than google 2020 redditWebSep 12, 2024 · CXCL13 is a chemokine that is widely involved in the pathogenesis of autoimmune diseases, tumors and inflammatory diseases. In this study, we investigate the role of CXCL13 in the pathogenesis of inflammatory bowel disease using both clinical specimens and animal models. We found that the serum CXCL13 concentration in IBD … is bing better or chromeWebAug 9, 2024 · CXCL13 (chemokine (C-X-C motif) ligand 13) is a B cell chemokine demonstrated to drive aggregate formation in tertiary lymphoid structures in mouse models of AAD , and CXCL12 has been demonstrated to be important in distinct lung inflammatory models . MMP-12 can modulate the activity of CXC chemokines by proteolytic processing . is bing better than edge