Web5 de jun. de 2024 · For HIF1-α, the optimal cutoff value was 7.17-fold change giving 80% sensitivity and 84% specificity and area under the curve (AUC) equivalent to 0.83, whereas for HIF1A-AS2 and LINK-A, the optimal cutoff values were 7.83- and 0.28-fold change giving 80% and 92% sensitivity and 82% and 94% specificity, with AUC equivalent to 0.867 and … Web15 de jun. de 2024 · MYC activates different metabolic programs in a cell-type- and cell-status-dependent manner. However, the role of MYC in inflammatory macrophages has not yet been determined. Metabolic and molecular analyses reveal that MYC, but not hypoxia inducible factor 1 (HIF1), is involved in enhancing early g …
Hypoxia-inducible factor - Wikipedia
WebAlternative Name: HIF1; HIF-1A; HIF1A; HIF-1-alpha; HIF1-alpha; BHLHE78; MOP1; PASD8 Reactivity: Human (QC Testing) Isotype: Mouse IgG1, κ Immunogen: Human … WebHIF パスウェイを阻害または活性化する化合物をご紹介します. 細胞内が低酸素状態に陥った際に活性化される転写因子 HIF(Hypoxia Inducible Factor)のシグナル伝達経 … dinner rolls bon appetit
Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by …
Web(Microbial infection) Upon infection by human coronavirus SARS-CoV-2, is required for induction of glycolysis in monocytes and the consequent pro-inflammatory state (PubMed:32697943). In monocytes, induces expression of ACE2 and cytokines such as IL1B, TNF, IL6, and interferons (PubMed:32697943). Promotes human coronavirus … WebHypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of a 120-kD HIF1-alpha subunit complexed with a 91- to 94-kD HIF1-beta subunit ( Wang et al., 1995 ). Web8 de jul. de 2024 · Cancer is a catastrophic disease that seriously affects human health. HIF1 α plays an important role in cancer initiation, progression, and prognosis. However, little is known about the specific role of HIF1 α in pan-cancer. Therefore, we systematically and comprehensively analyzed HIF1 α using GEPIA, HPA, GeneMANIA, STRING, … fortran cycle用法