Rel homology region
WebFeb 1, 1994 · Europe PMC is an archive of life sciences journal literature. WebThe rel family of proteins can be defined as a group of proteins that share sequence homology over a 300 amino acid region termed the rel domain. The rel family comprises …
Rel homology region
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WebNov 16, 2000 · The Rel homology region (RHR) is known to be important both for dimerization of NF-κB/Rel subunits (Grimm and Baeuerle, 1993), as well as for interaction … WebDec 31, 2013 · NF-κB itself belongs to the family of Rel-proteins containing the conserved Rel-homology-region, which encompasses 300 residues that fold into two immunoglobulin-like domains ,. Both of these domains are involved in DNA-binding, but dimerization of Rel-proteins is exclusively mediated by the C-terminally localized, shorter domain (Rel-C).
WebHomeoboks je sekvenca DNK, od oko 180 baznih parova, u genima koji su uključeni u regulaciju obrazaca anatomskog razvoja (morfogeneza) u životinja, gljiva, biljaka i brojnih jednoćelijskih eukariota. Geni Homeoboksni geni kodiraju homeodomenske proteinske proizvode koji su faktori transkripcije sa karakterističninom strukturom sklapanja proteina … WebFeb 1, 1996 · The defining characteristic of Rel proteins is a stretch of roughly 300 amino acids called the Rel homology region (RHR) or Rel homology domain (RHD), within which …
WebJun 22, 1999 · The Rel homology region of NFAT5 showed 41–45% identity with NFAT1–4 and 15–17% identity with p50 NF-κB in pairwise comparisons (Fig. 2 a and b), indicating … WebMar 21, 2024 · The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex.
WebThe sequence of this region of NFATp shows a low degree of similarity to the Rel homology region. One specific short sequence in NFATp (RAHYETEG), located near the NH2 …
The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene. The c-Rel protein is a member of the NF-κB family of transcription factors and contains a Rel homology domain (RHD) at its N-terminus and two C-terminal transactivation domains. c-Rel is a myeloid checkpoint protein that can be targeted for treating cancer. c-Rel has an important role in B-cell survival and pr… cmc computers southingtoncadillac xts v-sport for saleWebJan 9, 2024 · Further, we show by overexpression of truncated proteins that the catalytic USP domain of USP48 interacts with the N-terminal region of the Rel homology domain (RHD) of RelA. This study provides first evidence that the USP domain of USP48 is important for the physical association with substrate proteins, and a suitable target for small … cmc computers materialsWebTranscription factors bind to either enhancer or promoter regions of DNA adjacent to the genes that they regulate. ... 4.1 Class: RHR (Rel homology region) 4.1.1 Family: Rel/ankyrin; NF-kappaB; 4.1.2 Family: ankyrin only; 4.1.3 Family: NFAT (Nuclear Factor of Activated T-cells) (NFATC1, NFATC2, NFATC3) 4.2 Class: STAT cadillac xts weightWebAll these proteins share a highly conserved 300 aa Rel homology region (RHR), which is responsible for dimer-ization, DNA-binding and interaction with the inhibitory IκB proteins. cmc common mode chokeWebAug 31, 2003 · The crystal structure of the NFAT1 Rel homology region (RHR) bound to a pseudo-palindromic DNA site reveals an asymmetric dimer interaction between the RHR-C … cadillac xts touch screen replacement costWebFeb 1, 1994 · Within the Rel homology region of NF-kappa B p50 (also known as KBF1), two amino acid residues were identified by photocrosslinking to adjacent bases in a beta … cadillac xts sedan accelerate faster